MIF-IN-3bb |CAS:1663475-35-1 Probechem Biochemicals

Chemical Structure : MIF-IN-3bb

MIF-IN-3bb

Catalog No.: PC-63120Not For Human Use, Lab Use Only.

MIF-IN-3bb is a potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with Ki of 57 nM.

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Biological Activity

MIF-IN-3bb is a potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with Ki of 57 nM.
MIF-IN-3bb displays >1000-fold more active than the well-studied (R)-ISO-1 and more than 200-fold more active than the chromen-4-one Orita-13.

Physicochemical Properties

M.Wt	442.406
Formula	C24H15FN4O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((2-(1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl)quinolin-5-yl)oxy)benzoic acid

References

1. Dziedzic P, et al. J Am Chem Soc. 2015 Mar 4;137(8):2996-3003.

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MIF-IN-3bb

Biological Activity

Physicochemical Properties

References

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