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KLK6 inhibitor 42

Chemical Structure : KLK6 inhibitor 42

CAS No.: 2370980-52-0

KLK6 inhibitor 42

Catalog No.: PC-38211Not For Human Use, Lab Use Only.

KLK6 inhibitor 42 is a first-in-class inhibitor of kallikrein‐related peptidase 6 (KLK6, IC50=1.57 uM) that promote the differentiation of OPCs into mature oligodendrocytes in vitro..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    KLK6 inhibitor 42 is a first-in-class inhibitor of kallikrein‐related peptidase 6 (KLK6, IC50=1.57 uM) that promote the differentiation of OPCs into mature oligodendrocytes in vitro.

    Physicochemical Properties

    M.Wt 328.796
    Formula C18H17ClN2O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 5 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(4-(Aminomethyl)phenyl)-3-hydroxy-2-naphthamide hydrochloride

    References

    1. Sabrina Aït Amiri, et al. J Med Chem. 2021 May 13;64(9):5667-5688.

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