BDK inhibitor BT3 | BDK inhibitor | Probechem Biochemicals

Chemical Structure : BDK inhibitor BT3

BDK inhibitor BT3 (BT3)

Catalog No.: PC-49379Not For Human Use, Lab Use Only.

BDK inhibitor BT3 is a small molecule allosteric inhibitor of BCKDC kinase (BDK).

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Biological Activity

BDK inhibitor BT3 is a small molecule allosteric inhibitor of BCKDC kinase (BDK, branched-chain ketoacid dehydrogenase kinase).
BT3 significantly increase BCKDC activity in wild-type and MSUD cells.
BT3 is a prodrug of BT2 is more efficient than BT2 itself in enhancing BCKDC activity at the cellular level.

Physicochemical Properties

M.Wt	371.192
Formula	C13H8Cl2N4O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-acetamido-1,2,5-oxadiazol-3-yl)-3,6-dichlorobenzo[b]thiophene-2-carboxamide

References

1. Shih-Chia Tso, et al. J Biol Chem. 2014 Jul 25;289(30):20583-93.

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BDK inhibitor BT3 (BT3)

Biological Activity

Physicochemical Properties

References

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