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UCP0054278

Chemical Structure : UCP0054278

CAS No.: 52346-00-6

UCP0054278 (DJ-1 inhibitor compound B)

Catalog No.: PC-22172Not For Human Use, Lab Use Only.

DJ-1 inhibitor comp-23 is a small molecule binding to DJ-1 (PARK7) with binding Kd of 1.33 uM, inhibits oxidative stress-induced cell death of human dopaminergic neuroblastoma cell line SH-SY5Y cells at 1 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DJ-1 inhibitor comp-23 is a small molecule binding to DJ-1 (PARK7) with binding Kd of 1.33 uM, inhibits oxidative stress-induced cell death of human dopaminergic neuroblastoma cell line SH-SY5Y cells at 1 uM.

Physicochemical Properties

M.Wt 449.50
Formula C26H27NO6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(3-(benzyloxy)-4-methoxyphenyl)-N-(2-(7-methoxybenzo[d][1,3]dioxol-5-yl)ethyl)acetamide

References

1. Shin Miyazaki, et al. J Neurochem. 2008 Jun 1;105(6):2418-34.

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