Chemical Structure : Padsevonil
CAS No.: 1294000-61-5
Catalog No.: PC-35479Not For Human Use, Lab Use Only.
Padsevonil (UCB0942) is an antiepileptic drug (AED) candidate with high affinity for synaptic vesicle 2 (SV2) proteins with pKi of 8.5/7.9/8.5 for SV2A/SV2B/SV2C, respectively.
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M.Wt | 432.794 | |
Formula | C14H14ClF5N4O2S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(R)-4-(2-chloro-2,2-difluoroethyl)-1-((2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl)methyl)pyrrolidin-2-one |
1. Serrano E, et al. F1000Prime Rep. 2015 May 26;7:61.
2. Zaccara G, et al. Pharmacol Res. 2016 Feb;104:38-48.
3. Wood M, et al. J Pharmacol Exp Ther. 2020. PMID: 31619465
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