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Cimlanod

Chemical Structure : Cimlanod

CAS No.: 1620330-72-4

Cimlanod (BMS-986231, CXL-1427)

Catalog No.: PC-35441Not For Human Use, Lab Use Only.

Cimlanod is a second-generation nitroxyl (HNO) donor, delivers HNO via pH-dependent chemical breakdown when exposed to the neutral pH environment of the bloodstream, shows positive lusitropic and inotropic as well as vasodilatory effects.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Cimlanod (BMS-986231, CXL-1427) is a second-generation nitroxyl (HNO) donor, delivers HNO via pH-dependent chemical breakdown when exposed to the neutral pH environment of the bloodstream, shows positive lusitropic and inotropic as well as vasodilatory effects.

Physicochemical Properties

M.Wt 177.174
Formula C5H7NO4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-hydroxy-5-methylfuran-2-sulfonamide

References

1. Cowart D, et al. J Clin Pharmacol. 2019 May;59(5):717-730. 

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