Chemical Structure : MID-1
CAS No.: 312608-54-1
Catalog No.: PC-35530Not For Human Use, Lab Use Only.
MID-1 (ChemBridge5655896) is a specific small molecule MG53-IRS-1 interaction disruptor (MID), but not MG53-FAK and-Cav-3 interaction.
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10 mg | $198 | In stock | |
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50 mg | $528 | In stock | |
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MID-1 (ChemBridge5655896) is a specific small molecule MG53-IRS-1 interaction disruptor (MID), but not MG53-FAK and-Cav-3 interaction.
MID-1 increases the IRS-1 protein level in C2C12 myotubes, abrogates MG53-induced IRS-1 ubiquitination and degradation.
MID-1 potentially sensitizes insulin signaling with an elevated level of IRS-1 in skeletal muscle, enhances C2C12 myogenesis.
M.Wt | 293.30 | |
Formula | C12H11N3O4S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-Ethoxy-N-(5-nitrothiazol-2-yl)benzamide |
1. Lee H, et al. J Biol Chem. 2016 Dec 23;291(52):26627-26635.
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