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Chemical Structure : (R)-ND-336
Catalog No.: PC-35659Not For Human Use, Lab Use Only.
(R)-ND-336 is a potent and selective small-molecule MMP-9 inhibitor with Ki of 19 nM, weakly inhibits MMP-2 and MMP-14 (Ki=127 and 119 nM), poorly inhibits other MMPs (Ki>10 uM).
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(R)-ND-336 is a potent and selective small-molecule MMP-9 inhibitor with Ki of 19 nM, weakly inhibits MMP-2 and MMP-14 (Ki=127 and 119 nM), poorly inhibits other MMPs (Ki>10 uM).
(R)-ND-336 demonstrates superior efficacy in wound healing over becaplermin in vivo.
| M.Wt | 371.894 | |
| Formula | C16H18ClNO3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Nguyen TT, et al. J Med Chem. 2018 Sep 27. doi: 10.1021/acs.jmedchem.8b01005.
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