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(S)-3,5-dihydroxyphenylglycine

Chemical Structure : (S)-3,5-dihydroxyphenylglycine

CAS No.: 162870-29-3

(S)-3,5-dihydroxyphenylglycine ((S)-3,5-DHPG)

Catalog No.: PC-27166Not For Human Use, Lab Use Only.

(S)-3,5-DHPG ((S)-3,5-dihydroxyphenylglycine) is a selective group I metabotropic glutamate receptors (mGluRs) agonist with Ki values of 0.9 μM and 3.9 μM for mGluR1a and mGluR5a, respectively, exhibits anxiolytic activity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

(S)-3,5-DHPG ((S)-3,5-dihydroxyphenylglycine) is a selective group I metabotropic glutamate receptors (mGluRs) agonist with Ki values of 0.9 μM and 3.9 μM for mGluR1a and mGluR5a, respectively, exhibits anxiolytic activity.

Physicochemical Properties

M.Wt 183.16
Formula C8H9NO4:
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-2-amino-2-(3,5-dihydroxyphenyl)acetic acid

References

1. V Mutel, et al. J Neurochem. 2000 Dec;75(6):2590-601.

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