Chemical Structure : (S)-ACE-OH
Catalog No.: PC-23383Not For Human Use, Lab Use Only.
(S)-ACE-OH is a metabolite of acepromazin, acts as a molecular glue to induce an interaction between the E3 ubiquitin ligase TRIM21 and the nucleoporin NUP98, leading to the degradation of nuclear pore proteins and disruption of nucleocytoplasmic trafficking.
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(S)-ACE-OH is a metabolite of acepromazin, acts as a molecular glue to induce an interaction between the E3 ubiquitin ligase TRIM21 and the nucleoporin NUP98, leading to the degradation of nuclear pore proteins and disruption of nucleocytoplasmic trafficking.
M.Wt | 328.47 | |
Formula | C19H24N2OS | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Panrui Lu, et al. Cell. 2024 Oct 30:S0092-8674(24)01197-8.
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