Chemical Structure : (S)-CKi-1
CAS No.: 2768295-41-4
Catalog No.: PC-20156Not For Human Use, Lab Use Only.
(S)-CKi-1 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.6 uM, depletes creatine phosphagen energetics in cells.
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(S)-CKi-1 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.6 uM, depletes creatine phosphagen energetics in cells.
M.Wt | 254.67 | |
Formula | C11H11ClN2O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(S)-4-(2-chloroacetyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxamide |
1. Narek Darabedian, et al. Nat Chem Biol. 2023 Feb 23. doi: 10.1038/s41589-023-01273-x.
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