(S)-CKi-1 | Covalent creatine kinase inhibitor

Chemical Structure : (S)-CKi-1

CAS No.: 2768295-41-4

(S)-CKi-1 (CKi-24)

Catalog No.: PC-20156Not For Human Use, Lab Use Only.

(S)-CKi-1 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.6 uM, depletes creatine phosphagen energetics in cells.

Packing	Price	Stock
2 mg	$358	In stock
5 mg	$558	In stock
10 mg	$898	In stock
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Biological Activity

(S)-CKi-1 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.6 uM, depletes creatine phosphagen energetics in cells.

Physicochemical Properties

M.Wt	254.67
Formula	C11H11ClN2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-4-(2-chloroacetyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxamide

References

1. Narek Darabedian, et al. Nat Chem Biol. 2023 Feb 23. doi: 10.1038/s41589-023-01273-x.

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(S)-CKi-1 (CKi-24)

Biological Activity

Physicochemical Properties

References

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