066ATZ

You are here:Home-Chemical Inhibitors & Agonists-Others-Other Targets-066ATZ

Chemical Structure : 066ATZ

Catalog No.: PC-26909Not For Human Use, Lab Use Only.

066ATZ is a potent, selective dual PIP4K2A and PIP4K2B inhibitor with Ki of 100 nM and 800 nM.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

066ATZ is a potent, selective dual PIP4K2A and PIP4K2B inhibitor with Ki of 100 nM and 800 nM.
066ATZ displays selectivity over a panel of protein and lipid kinases。
066ATZ inhibits two closely related protein kinases, CK2a and CK2a2 (casein kinase 2 catalytic subunits α and α′ with Ki ∼130 nM and 40 nM, respectively.
066ATZ binds to ATP-binding sites of PIP4K2A and PIP4K2B to block lipid kinase activity.
066ATZ reduces tumor growth rate in a xenograft model of NSCLC.

Physicochemical Properties

M.Wt	489.56
Formula	C22H23N11OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-2-((5-(1H-tetrazol-5-yl)thiazol-2-yl)amino)-8-cyclopentyl-5-methyl-7-(pyridin-2-ylmethyl)-7,8-dihydropteridin-6(5H)-one

References

1. He Z, et al. iScience. 2026 Apr 30;29(6):115952.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

066ATZ

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.