1,4-DPCA

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Chemical Structure : 1,4-DPCA

CAS No.: 331830-20-7

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Catalog No.: PC-25242Not For Human Use, Lab Use Only.

1,4-DPCA is a potent prolyl-4-hydroxylase (P4H) inhibitor, inhibits collagen hydroxylation in human foreskin fibroblasts with IC50 of 2.4 µM, inhibits prolyl-4-hydroxylases α isoforms stabilizes HIF-1α protein.

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10 mg	$78	In stock
25 mg	$128	In stock
50 mg	$198	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	240.22
Formula	C13H8N2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-Oxo-4,4a-dihydro-1,10-phenanthroline-3-carboxylic acid

References

1. Yong Zhang, et al. Sci Transl Med. 2015 Jun 3;7(290):290ra92.

2. Gaofeng Xiong, et al. BMC Cancer. 2014 Jan 2;14:1.

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1,4-DPCA

Biological Activity

Physicochemical Properties

References

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