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Cat. No. Product Name CAS No. Information
PC-38083

Izilendustat

1303512-02-8 Izilendustat is a potent inhibitor of HIF prolyl hydroxylase (PHD) which stabilizes hypoxia inducible factor- 1 alpha (HIF- lα), as well as hypoxia inducible factor-2 (HIF-2)..
PC-62044

KHS-101

1262770-73-9 KHS-101 (KHS101) is a small molecule that selectively induces a neuronal differentiation phenotype, induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3 (EC50=1 uM).
PC-61213

JNJ-42905343

1238689-36-5 JNJ-42905343 is a potent, selective, orally active prolyl hydroxylase (PHD) inhibitor with pKi of 8.07, 7.48 and 7.27 for PHD1, PHD2 and PHD3 respectively.
PC-60509

Desidustat

1616690-16-4 Desidustat (ZYAN1) is a novel HIF prolyl hydroxylase (PHD) inhibitor under clinical development for the treatment of anemia.
PC-60370

IDF-11774

1429054-28-3 IDF-11774 (IDF 11774, IDF11774) is a potent, orally bioavailable HIF-1 inhibitor that reduces the HRE-luciferase activity of HIF-1α (IC50=3.65 uM) and blocks HIF-1α accumulation under hypoxia in HCT116 human colon cancer cells.
PC-60317

PT-2399

1672662-14-4 PT-2399 (PT 2399, PT2399) is a selective, potent HIF-2α antagonist that binds directly to the HIF2α PAS B domain.
PC-45660

THS-044

62054-67-5 THS-044 is a low micromolar HIF2α PAS-B binding compound (Kd=2 uM).

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