Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Nuclear Receptor/Transcription Factor-HIF/HIF Prolyl-hydroxylase

Request The Product List ofHIF/HIF Prolyl-hydroxylase HIF/HIF Prolyl-hydroxylase

Cat. No. Product Name Information
PC-42229

SYP-5

HIF-1 inhibitor

SYP-5 is a potent HIF-1 inhibitor that inhibits hypoxia-induced upregulation of HIF-1, suppresses tumor cells invasion and angiogenesis.
PC-45387

Daprodustat

HIF-PHD inhibitor

Daprodustat (GSK1278863) is a potent, orally active HIF-prolyl hydroxylase (PHD) inhibitor with IC50 of 3.5, 22.2 and 2.2 nM for PHD1, PHD2 and PHD3, respectively.
PC-25040

Davotifan

HIF-2α inhibitor

Davotifan is a potent, selective HIF-2α inhibitor.
PC-24681

HIF-1α inhibitor LW6

HIF-1α inhibitor

HIF-1α inhibitor LW6 is a specific small compound that inhibits the accumulation of HIF-1α, decreases HIF-1α protein expression without affecting HIF-1β expression, has IC50 of 2.6 uM in HIF-1-mediated cell-based reporter assay in Hep3B cells.
PC-24485

HIF-PH inhibitor 13

HIF-PH inhibitor

HIF-PH inhibitor 13 is a potent, orally bioavailable hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor with IC50 of 0.1 uM (PHD2).
PC-24484

M1002

HIF-2 agonist

M1002 is a small molecule allosteric agonist of hypoxia-inducible factor-2 (HIF-2) with EC50 of 0.44 uM in luciferase reporter gene assays, enhances the affinity of HIF-2α and ARNT for transcriptional activation.
PC-24483

ZG-2033

HIF-2α agonist

ZG-2033 is a potent, selective and orally bioavailable HIF-2α agonist with EC50 of 490 nM, Emax = 349.2%.
PC-24421

PRLX 93936

HIF-1α inhibitor

PRLX 93936 (PRLX-93936) is a potent small molecule inhibitor of HIF-1α transcriptional factor with IC50 of 0.09 uM, shows with broad antitumor activity in vitro.
PC-23636

Takeda-17

PHD inhibitor

Takeda-17 (PHD-1 inhibitor 17) is a potent, selective inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) with IC50 of 34 nM.
PC-23635

JPHM-2-167

PHD inhibitor

JPHM-2-167 is a potent, selective prolyl hydroxylase (PHD) inhibitor with IC50 of 1.7, 2.1 and 11 nM for PHD1, PHD2, and PHD3 respectively.
PC-23634

DDO-3055

PHD inhibitor

DDO-3055 is a potent, selective prolyl hydroxylase (PHD) inhibitor with IC50 of 64.2 nM toward PHD2, 29- and 2.6-fold selective over PHD1 and PHD3.
PC-22855

DS-1093a

HIF-PHD inhibitor

DS-1093a is a potent, selective and oral hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) inhibitor with EC50 of 0.49 uM (EPO production in Hep3B cells).

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com