JPHM-2-167

Chemical Structure : JPHM-2-167

Catalog No.: PC-23635Not For Human Use, Lab Use Only.

JPHM-2-167 is a potent, selective prolyl hydroxylase (PHD) inhibitor with IC50 of 1.7, 2.1 and 11 nM for PHD1, PHD2, and PHD3 respectively.

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Biological Activity

JPHM-2-167 is a potent, selective prolyl hydroxylase (PHD) inhibitor with IC50 of 1.7, 2.1 and 11 nM for PHD1, PHD2, and PHD3 respectively.

M.Wt	504.59
Formula	C30H28N6O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-([1,1'-biphenyl]-4-yl)-8-((3-methylpyridin-2-yl)methyl)-1-(pyrimidin-2-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione

1. Vachal P, et al. J Med Chem. 2012 Apr 12;55(7):2945-59.