HIF/HIF Prolyl-hydroxylase (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofHIF/HIF Prolyl-hydroxylase HIF/HIF Prolyl-hydroxylase

Cat. No.	Product Name	Information
PC-22619	ZG-2291 FIH inhibitor	ZG-2291 is a highly potent, selective and in vivo active factor inhibiting HIF (FIH) inhibitor with Ki of 65.3 nM, 39-fold selective over PHD2.
PC-22355	DS44470011 HIF-PHD inhibitor	DS44470011 is a potent, selective hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) inhibitor with IC50 of 1.5 uM for HIF-PHD2, induces erythropoietin (EPO) release in Hep3B cells with EC50 of 8.4 uM.
PC-22353	PHD inhibitor IOX5 HIF-PHD inhibitor	IOX5 is a potent, selective HIF-prolyl hydroxylase (PHD) inhibitor with IC50 of 0.15 uM ((PHD2), does not inhibit other 2OG-dependent oxygenases (JMJD6, FIH, KDM6B etc.).
PC-22317	TC-S7009 HIF2α inhibitor	TC-S7009 is a specific inhibitor of HIF-2α with Kd of 81 nM, disrupts HIF-2α′s heterodimerization and DNA-binding activity, reducing the expression of HIF-2α-dependent genes.
PC-21729	FG-0041 HIF-PH inhibitor	FG-0041 (FG0041) is a small molecule inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) with IC50 of 2 uM for collagen prolyl hydroxylase.

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