CP4.29

Chemical Structure : CP4.29

Catalog No.: PC-26782Not For Human Use, Lab Use Only.

CP4.29 is a pharmacological agent that re-folds and re-activates mutant pVHL, bind to the folded (native) conformation of pVHL and stabilize it, restores wild-type pVHL activities to cells that harbor mutant VHL, induces VHL-dependent depletion of HIF-2α.

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Biological Activity

Physicochemical Properties

M.Wt	421.32
Formula	C20H22Cl2N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(3,5-dichloro-1H-indol-2-yl)(4-((3-isopropyl-1,2,4-oxadiazol-5-yl)methyl)piperidin-1-yl)methanone

References

1. Fouad MA, et al. bioRxiv [Preprint]. 2026 May 10:2026.01.02.697373.

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CP4.29

Biological Activity

Physicochemical Properties

References

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