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KRH102140

Chemical Structure : KRH102140

CAS No.: 864769-01-7

KRH102140 (KRH-102140)

Catalog No.: PC-26847Not For Human Use, Lab Use Only.

KRH-102140 is a potent small molecule inhibitor of 5-lipoxygenase (5-LO) with IC50 of 160 nM for LTB(4) inhibition in RBL-1 cells.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

KRH-102140 is a potent small molecule inhibitor of 5-lipoxygenase (5-LO) with IC50 of 160 nM for LTB(4) inhibition in RBL-1 cells.

Physicochemical Properties

M.Wt 373.47
Formula C25H24FNO
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2-fluoro-benzyl)-(2-methyl-2-phenethyl-2H-chromen-6-yl)-amine

References

1. Cho YS, et al. Pharmacology. 2011;87(1-2):49-55.

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