THS-044 |CAS:62054-67-5 Probechem Biochemicals

Chemical Structure : THS-044

CAS No.: 62054-67-5

Catalog No.: PC-45660Not For Human Use, Lab Use Only.

THS-044 is a low micromolar HIF2α PAS-B binding compound (Kd=2 uM).

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Biological Activity

THS-044 is a low micromolar HIF2α PAS-B binding compound (Kd=2 uM), modulates the affinity of the HIF2α:ARNT PAS-B heterodimer in vitro.

M.Wt	291.2265
Formula	C11H12F3N3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-Morpholinamine, N-[2-nitro-4-(trifluoromethyl)phenyl]-

1. Scheuermann TH, et al. Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):450-5.

2. Motto I, et al. J Chem Inf Model. 2011 Nov 28;51(11):2868-81.