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Chemical Structure : 1-Piperidine Propionic Acid
CAS No.: 26371-07-3
Catalog No.: PC-21762Not For Human Use, Lab Use Only.
1-Piperidine Propionic Acid (1-PPA) is an allosteric Inhibitor of protease activated receptor-2 (PAR2) with IC50 of 2.3 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $198 | In stock | |
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| 100 mg | Get quote |
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1-Piperidine Propionic Acid (1-PPA) is an allosteric Inhibitor of protease activated receptor-2 (PAR2) with IC50 of 2.3 uM.
1-PPA binds PAR2 in an allosteric pocket of the receptor inactive conformation.
1-PPA reduces platelet aggregation, inhibits the PAR2-C/EBP-β-SerpinB3 axis and protects from NASH development and progression.
| M.Wt | 157.21 | |
| Formula | C8H15NO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-(piperidin-1-yl)propanoic acid |
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1. Villano Gianmarco, et al. Mol Metab. 2024 Feb 1:81:101889.
2. Chinellato M, et al. Pharmaceuticals (Basel). 2023 Oct 18;16(10):1486.
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