10074-A4

Chemical Structure : 10074-A4

CAS No.: 312631-87-1

Catalog No.: PC-21473Not For Human Use, Lab Use Only.

10074-A4 is a specific small molecule inhibitor of c-Myc370-409 with binding Kd of 36.3 uM.

Packing	Price	Stock
5 mg	$188	In stock
10 mg	$288	In stock
25 mg	$428	In stock
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Biological Activity

10074-A4 is a specific small molecule inhibitor of c-Myc 370-409 with binding Kd of 36.3 uM.
10074-A4 inhibits the mRNA level of the c-Myc target genes, CCND2 and CDK4.
10074-A4 arrests the cell cycle at the S-phase, shows inhibitory activity of HL-60 cells with IC50 of 15.1 uM.

Physicochemical Properties

M.Wt	409.28
Formula	C18H14Cl2N2O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(3-(3,6-dichloro-9H-carbazol-9-yl)-2-hydroxypropyl)thiazolidine-2,4-dione

References

1. Chen Yu, et al. Sci Rep. 2016 Mar 2;6:22298.

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10074-A4

Biological Activity

Physicochemical Properties

References

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