| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-38435 |
3JC48-3
|
1629989-75-8 |
3JC48-3 is a potent, cellularly active and stable c-Myc inhibitor, inhibits c-Myc-max dimerization with IC50 of 34 uM, 5 times more potent than 10074-G5, exhibits an approximate twofold selectivity for c-Myc-Max heterodimers over Max-Max homodimers. |
| PC-35303 |
MYCMI-6
|
681282-09-7 |
MYCMI-6 (NSC354961) is a selective, high affinity inhibitor of MYC-MAX interaction, blocks MYC-driven transcription and binds selectively to the MYC bHLHZip domain with Kd of 1.6 uM in SPR assay. |
| PC-60543 |
CBL0137
|
1197996-80-7 |
CBL0137 (Curaxin CBL0137) is a histone chaperone FACT (facilitates chromatin transcription) and MYC signal inhibitor that markedly reduced tumor initiation and progression in vivo. |
| PC-60241 |
sAJM-589
|
2089-82-9 |
sAJM-589 is a novel, potent small molecule Myc inhibitor that disrupts the Myc-Max leucine-zipper heterodimer with IC50 of 1.8 uM. |
| PC-38695 |
MYRA-B
|
307326-46-1 |
MYRA-B (NSC45641) is a small molecule that induces Myc-dependent apoptosis without affecting Myc transactivation or Myc/Max DNA binding. |
| PC-38694 |
MYRA-A
|
3900-43-4 |
MYRA-A (NSC339585) is a small molecule Myc pathway response agent (MYRA) that inhibits Myc transactivation and interferes with the DNA-binding activity of Myc family proteins, with no effect on the E-box-binding protein USF. |
| PC-38693 |
KSI-3716
|
1151813-61-4 |
KSI-3716 is a small molecule c-MYC inhibitor that blocks c-MYC/MAX binding to target gene promoters, inhibits c-MYC mediated transcriptional activity at concentrations as low as 1 uM. |
