Cat. No. |
Product Name |
Information |
PC-38661 |
L755507
c-Myc-MAX inhibitor
|
L755507 is a potent, selective β3-adrenoceptor (β3-AR) agonist, exhibits robust concentration-dependent increase in cAMP accumulation in CHO-K1 cells expressing human β3-adrenoceptors (pEC50=12.3), also effectively inhibits the c-Myc-MAX heterodimerization. |
PC-38523 |
F1021-0686
c-Myc inhibitor
|
F1021-0686 is a novel small molecule inhibitor of c-Myc, causes the functional repression of c-Myc target gene, shows appreciable anticancer activity against c-Myc expressing cell lines (HT29, IC50=1.55 uM). |
PC-38522 |
F0909-0360
c-Myc inhibitor
|
F0909-0360 is a novel small molecule inhibitor of c-Myc, causes the functional repression of c-Myc target gene, shows appreciable anticancer activity against c-Myc expressing cell lines (HT29, IC50=0.2 uM). |
PC-38503 |
Mycro3
Myc inhibitor
|
Mycro3 is a selective small molecule inhibitor of Myc/Max dimerization with IC50 of 40 uM with a cognate-binding site, inhibits DNA binding of c-Myc with preference over other dimeric transcription factors in vitro. |
PC-73141 |
MYC inhibitor EN4
MYC covalent inhibitor
|
MYC inhibitor EN4 is a covalent ligand and inhibitor of MYC, targets cysteine 171 of MYC and inhibits MYC transcriptional activity (EC50=2.8 uM). |
PC-72923 |
WBC100
c-Myc inhibitor
|
WBC100 (WBC-100) is a novel potent, oral active that selectively degrades c-Myc protein over other proteins and potently kills c-Myc overexpressing cancer cell. |
PC-72260 |
PKUMDL-YC-1205
c-Myc inhibitor
|
PKUMDL-YC-1205 is a specific small molecule that can specifically bind to the disordered bHLH-LZ domain of c-Myc (SPR kd=18 uM). |
PC-35731 |
MYC inhibitor DC-34
|
MYC inhibitor DC-34 is a potent small molecule that selectively inhibits MYC at the transcriptional level only when a G-quadruplex (G4) is present in the promoter, binds to MYC G4 with Kd of 9.4 uM. |
PC-35076 |
APTO-253 hydrochloride
|
APTO-253 is a small molecule inducer of KLF4, stabilizes G-quadruplex DNA and reduces MYC mRNA expression and protein levels. |
PC-61770 |
BTYNB
|
BTYNB is a potent and selective inhibitor of IMP1 binding to c-Myc mRNA with IC50 of 5 uM. |
PC-61359 |
IRES-C11
|
A novel, spectfic c-Myc IRES (internal ribosome entry site) function inhibitor that prevents binding of hnRNP A1 to the Myc IRES and specifically inhibits Myc IRES activity in MM cells. |
PC-70283 |
Stauprimide
|
A staurosporine analog that promotes embryonic stem cell (ESC) differentiation by inhibiting nuclear localization of the MYC transcription factor NME2, which in turn results in down-regulation of MYC transcription. |