Chemical Structure : PKUMDL-YC-1205
CAS No.: 132388-59-1
Catalog No.: PC-72260Not For Human Use, Lab Use Only.
PKUMDL-YC-1205 is a specific small molecule that can specifically bind to the disordered bHLH-LZ domain of c-Myc (SPR kd=18 uM).
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PKUMDL-YC-1205 is a specific small molecule that can specifically bind to the disordered bHLH-LZ domain of c-Myc (SPR kd=18 uM).
PKUMDL-YC-1205 abrogates cell proliferation of HL-60 cells with IC50 of 40 uM, blocks the interaction between c-Myc370–409 and Max.
M.Wt | 596.683 | |
Formula | C38H32N2O5 | |
Appearance | Solid | |
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1. Chen Yu, et al. Sci Rep. 2016 Mar 2;6:22298.
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