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PKUMDL-YC-1205

Chemical Structure : PKUMDL-YC-1205

CAS No.: 132388-59-1

PKUMDL-YC-1205

Catalog No.: PC-72260Not For Human Use, Lab Use Only.

PKUMDL-YC-1205 is a specific small molecule that can specifically bind to the disordered bHLH-LZ domain of c-Myc (SPR kd=18 uM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PKUMDL-YC-1205 is a specific small molecule that can specifically bind to the disordered bHLH-LZ domain of c-Myc (SPR kd=18 uM).
PKUMDL-YC-1205 abrogates cell proliferation of HL-60 cells with IC50 of 40 uM, blocks the interaction between c-Myc370–409 and Max.

Physicochemical Properties

M.Wt 596.683
Formula C38H32N2O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

References

1. Chen Yu, et al. Sci Rep. 2016 Mar 2;6:22298.

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