PKUMDL-YC-1205 | c-Myc inhibitor | Probechem Biochemicals

Chemical Structure : PKUMDL-YC-1205

CAS No.: 132388-59-1

PKUMDL-YC-1205 (c-Myc bHLH-LZ domain inhibitor)

Catalog No.: PC-72260Not For Human Use, Lab Use Only.

PKUMDL-YC-1205 is a specific small molecule that can specifically bind to the disordered bHLH-LZ domain of c-Myc (SPR Kd=18 uM).

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10 mg	$188	In stock
25 mg	$298	In stock
50 mg	$488	In stock
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Biological Activity

PKUMDL-YC-1205 is a specific small molecule that can specifically bind to the disordered bHLH-LZ domain of c-Myc (SPR Kd=18 uM).
PKUMDL-YC-1205 abrogates cell proliferation of HL-60 cells with IC50 of 40 uM, blocks the interaction between c-Myc370–409 and Max.

Physicochemical Properties

M.Wt	596.683
Formula	C38H32N2O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N4-trityl-L-asparagine

References

1. Chen Yu, et al. Sci Rep. 2016 Mar 2;6:22298.

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PKUMDL-YC-1205 (c-Myc bHLH-LZ domain inhibitor)

Biological Activity

Physicochemical Properties

References

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