| Cat. No. |
Product Name |
Information |
| PC-24710 |
M606
MYCN inhibitor, Iron chelator
|
M606 is a selective, iron-chelating small molecule inhibitor of MYCN/c-Myc, reduces MYCN protein expression by acting on the MYCN promoter via E2F3-mediated transcription factor binding sites. |
| PC-24270 |
MI202
MYCN expression inhibitor
|
MI202 is a potent inhibitor of MYCN expression, inhibits both MYCN promoter activity (IC50=2.21 μM) and endogenous MYCN expression (IC50=1.07 μM) in JHH7 cells, through ACOT2-mediated signaling pathways. |
| PC-24225 |
MY05
c-Myc inhibitor
|
MY05 is a specific small molecule inhibitor of c-MYC, disrupts MYC-MAX interaction, induces reduced levels of active MYC. |
| PC-23437 |
NY2267
c-Myc inhibitor
|
NY2267 is a small molecule inhibitor of Myc-Max dimerization with IC50 of 36.5 uM in EMSA assays, inhibits Myc-induced oncogenic transformation in cell culture. |
| PC-23436 |
Mycro2
c-Myc inhibitor
|
Mycro2 is a selective small molecule inhibitor of c-Myc/Max dimerization with IC50 of 23 uM, inhibits c-Myc dependent transcription. |
| PC-23435 |
Mycro1
c-Myc inhibitor
|
Mycro1 is a selective small molecule inhibitor of c-Myc/Max dimerization with IC50 of 30 uM, inhibits c-Myc dependent transcription. |
| PC-23434 |
D347-2761
c-Myc inhibitor
|
D347-2761 is a small molecule c-Myc inhibitor, blocks c-Myc/Max heterodimer and disturbs c-Myc protein stability simultaneously, inhibits c-Myc-mediated transcriptional activities. |
| PC-21524 |
Isopomiferin
MYCN inhibitor
|
Isopomiferin is a prenylated isoflavonoid, collapses the tumor checkpoint module (TCM) and suppresses both MYCN and TEAD4 in MYCN-amplified NBL cells. |
| PC-21473 |
10074-A4
c-Myc inhibitor
|
10074-A4 is a specific small molecule inhibitor of c-Myc370-409 with binding Kd of 36.3 uM. |
