MY05

Chemical Structure : MY05

Catalog No.: PC-24225Not For Human Use, Lab Use Only.

MY05 is a specific small molecule inhibitor of c-MYC, disrupts MYC-MAX interaction, induces reduced levels of active MYC.

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Biological Activity

MY05 is a specific small molecule inhibitor of c-MYC, disrupts MYC-MAX interaction, induces reduced levels of active MYC.
MY05 is significantly selective for MYC-expressing cells compared to MYC-nonexpressing cells.
MY05 engages and reduces MYC levels to frustrate the MYC transcriptional program.
MY05 (10 mg/kg) inhibits tumor progression in MDA-MB 468 TNBC mouse model.

Physicochemical Properties

M.Wt	346.77
Formula	C19H11ClN4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(4-chlorophenyl)-6-oxo-1-phenyl-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

References

1. Obisesan OA, et al. J Med Chem. 2025 Mar 12. doi: 10.1021/acs.jmedchem.4c02556.

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MY05

Biological Activity

Physicochemical Properties

References

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