| Cat. No. |
Product Name |
Information |
| PC-38522 |
F0909-0360
c-Myc inhibitor
|
F0909-0360 is a novel small molecule inhibitor of c-Myc, causes the functional repression of c-Myc target gene, shows appreciable anticancer activity against c-Myc expressing cell lines (HT29, IC50=0.2 uM). |
| PC-38503 |
Mycro3
Myc inhibitor
|
Mycro3 is a selective small molecule inhibitor of Myc/Max dimerization with IC50 of 40 uM with a cognate-binding site, inhibits DNA binding of c-Myc with preference over other dimeric transcription factors in vitro. |
| PC-38435 |
3JC48-3
c-Myc inhibitor
|
3JC48-3 is a potent, cellularly active and stable c-Myc inhibitor, inhibits c-Myc-max dimerization with IC50 of 34 uM, 5 times more potent than 10074-G5, exhibits an approximate twofold selectivity for c-Myc-Max heterodimers over Max-Max homodimers. |
| PC-73228 |
MYCMI-7
MYC-MAX inhibitor
|
MYCMI-7 is a small molecule MYC-binding compound (Kd=4 uM) that inhibits MYC-MAX interaction. |
| PC-73141 |
MYC inhibitor EN4
MYC covalent inhibitor
|
MYC inhibitor EN4 is a covalent ligand and inhibitor of MYC, targets cysteine 171 of MYC and inhibits MYC transcriptional activity (EC50=2.8 uM). |
| PC-73127 |
MYCi975
c-Myc inhibitor
|
MYCi975 (NUCC-0200975) is a close analog of MYCi361 with improved therapeutic index, binds to MYC protein with KD of 2.5 uM, disrupts MYC/MAX complex formation. |
| PC-73126 |
MYCi361
MYC inhibitor
|
MYCi361 (NUCC-0196361) is a small molecule MYC inhibitor, binds to MYC protein with KD of 3.2 uM, disrupts MYC/MAX complex formation. |
| PC-72931 |
VPC-70619
N-Myc inhibitor
|
VPC-70619 (VPC70619) is a selective small-molecule inhibitor of N-Myc transcription in NMYC transcription inhibition assays. |
| PC-72923 |
WBC100
c-Myc inhibitor
|
WBC100 (WBC-100) is a novel potent, oral active that selectively degrades c-Myc protein over other proteins and potently kills c-Myc overexpressing cancer cell. |
| PC-72260 |
PKUMDL-YC-1205
c-Myc inhibitor
|
PKUMDL-YC-1205 is a specific small molecule that can specifically bind to the disordered bHLH-LZ domain of c-Myc (SPR Kd=18 uM). |
| PC-35731 |
MYC inhibitor DC-34
Myc inhibitor
|
MYC inhibitor DC-34 is a potent small molecule that selectively inhibits MYC at the transcriptional level only when a G-quadruplex (G4) is present in the promoter, binds to MYC G4 with Kd of 9.4 uM. |
| PC-35303 |
MYCMI-6
MYC-MAX inhibitor
|
MYCMI-6 (NSC354961) is a selective, high affinity inhibitor of MYC-MAX interaction, blocks MYC-driven transcription and binds selectively to the MYC bHLHZip domain with Kd of 1.6 uM in SPR assay. |
