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KJ-Pyr-9

Chemical Structure : KJ-Pyr-9

CAS No.: 581073-80-5

KJ-Pyr-9 (KJ Pyr 9)

Catalog No.: PC-45695Not For Human Use, Lab Use Only.

KJ-Pyr-9 is a novel small-molecule inhibitor of c-Myc (Kd=6.5 ± 1.0 nM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

KJ-Pyr-9 is a novel small-molecule inhibitor of c-Myc (Kd=6.5 ± 1.0 nM).
KJ-Pyr-9 interferes with MYC-MAX complex formation and inhibits MYC-induced oncogenic transformation in cells.
KJ-Pyr-9 is active in xenograft mice.

Physicochemical Properties

M.Wt 385.3722
Formula C22H15N3O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzamide, 4-[2-(2-furanyl)-6-(4-nitrophenyl)-4-pyridinyl]-

References

1. Hart JR, et al. Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12556-61.

2. Raffeiner P, et al. Oncotarget. 2014 Oct 15;5(19):8869-78.

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