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MYRA-A

Chemical Structure : MYRA-A

CAS No.: 3900-43-4

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MYRA-A (NSC339585)

Catalog No.: PC-38694Not For Human Use, Lab Use Only.

MYRA-A (NSC339585) is a small molecule Myc pathway response agent (MYRA) that inhibits Myc transactivation and interferes with the DNA-binding activity of Myc family proteins, with no effect on the E-box-binding protein USF.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MYRA-A (NSC339585) is a small molecule Myc pathway response agent (MYRA) that inhibits Myc transactivation and interferes with the DNA-binding activity of Myc family proteins, with no effect on the E-box-binding protein USF.
    MYRA-A (NSC339585) (3 uM) induces c-Myc-dependent apoptosis by MYRAs in Rat-1 cell lines, predominantly suppresses the growth of Myc overexpressing Tet-Myc cells.

    Physicochemical Properties

    M.Wt 340.379
    Formula C19H20N2O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-((3-(dimethylamino)propyl)amino)-1,4-dihydroxyanthracene-9,10-dione

    References

    1. Hao Mo, et al. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6344-9.

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