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Chemical Structure : VPC-70063
CAS No.: 13571-44-3
Catalog No.: PC-49220Not For Human Use, Lab Use Only.
VPC-70063 (VPC70063) is a small molecule Myc inhibitor that inhibits Myc-Max transcriptional activity with IC50 of 8.9 uM in c-Myc luciferase reporter assay in LNCaP cells, disrupts the interaction of Myc-Max with DNA.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $138 | In stock | |
| 25 mg | $228 | In stock | |
| 50 mg | $388 | In stock | |
| 100 mg | Get quote |
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VPC-70063 (VPC70063) is a small molecule Myc inhibitor that inhibits Myc-Max transcriptional activity with IC50 of 8.9 uM in c-Myc luciferase reporter assay in LNCaP cells, disrupts the interaction of Myc-Max with DNA.
VPC-70063 inhibits Myc-driven cell proliferation of LNCaP cell with IC50 of 2.5 uM, with no significant effect on the c-Myc cells.
VPC-70063 inhibits Myc-Max downstream pathway using UBE2C reporter assay.
| M.Wt | 378.336 | |
| Formula | C16H12F6N2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(1-benzyl-3-(3,5-bis(trifluoromethyl)phenyl)thiourea) |
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1. Lavinia A Carabet, et al. Eur J Med Chem. 2018 Dec 5;160:108-119.
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