17β-HSD13-IN-1

Chemical Structure : 17β-HSD13-IN-1

Catalog No.: PC-27631Not For Human Use, Lab Use Only.

17β-HSD13-IN-1 is a potent, selective hydroxysteroid 17-β-dehydrogenase 13 (17β-HSD13) inhibitor with cell IC50 of 14 nM, has >3000-fold seletivity over 17β-HSD1.

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Biological Activity

17β-HSD13-IN-1 is a potent, selective hydroxysteroid 17-β-dehydrogenase 13 (17β-HSD13) inhibitor with cell IC50 of 14 nM, has >3000-fold seletivity over 17β-HSD1.

Physicochemical Properties

M.Wt	577.50
Formula	C25H26F7N5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-fluoro-4-hydroxy-N-(6-methyl-5-(3,3,3-trifluoro-1-(1-(1-(trifluoromethyl)cyclobutane-1-carbonyl)piperidin-4-yl)propyl)pyridin-2-yl)pyrimidine-2-carboxamide

References

1. Hugelshofer CL, et al. J Med Chem. 2026 Aug 13;69(15):18938-18951.

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17β-HSD13-IN-1

Biological Activity

Physicochemical Properties

References

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