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2,4-PDCA

Chemical Structure : 2,4-PDCA

CAS No.: 499-80-9

2,4-PDCA (2,4 pyridine dicarboxylic acid)

Catalog No.: PC-22357Not For Human Use, Lab Use Only.

2,4-PDCA (2,4 pyridine dicarboxylic acid) is a broad-spectrum inhibitor of 2OG oxygenases, including JmjC domain-containing family of histone demethylases (JHDMs), shows acceptable KDM5B inhibition in vitro, with an IC50 value of 3 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

2,4-PDCA (2,4 pyridine dicarboxylic acid) is a broad-spectrum inhibitor of 2OG oxygenases, including JmjC domain-containing family of histone demethylases (JHDMs), shows acceptable KDM5B inhibition in vitro, with an IC50 value of 3 uM.

Physicochemical Properties

M.Wt 167.12
Formula C7H5NO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2,4 pyridine dicarboxylic acid

References

1. Rose NR, et al. J Med Chem. 2008 Nov 27;51(22):7053-6.

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