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Chemical Structure : 22-Azacholesterol
Catalog No.: PC-62202Not For Human Use, Lab Use Only.
22-Azacholesterol is the first small molecule inhibitor that inhibits Hedgehog (Hh) signaling by binding the oxysterol-binding site of Smo, inhibits Sonic Hedgehog (Shh) signaling with IC50 of 3 uM in NIH-3T3 cells..
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22-Azacholesterol (22-NHC) is the first small molecule inhibitor that inhibits Hedgehog (Hh) signaling by binding the oxysterol-binding site of Smo, inhibits Sonic Hedgehog (Shh) signaling with IC50 of 3 uM in NIH-3T3 cells.
| M.Wt | 387.64 | |
| Formula | C26H45NO | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Nedelcu D, et al. Nat Chem Biol. 2013 Sep;9(9):557-64.
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