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25-Hydroxycholesterol

Chemical Structure : 25-Hydroxycholesterol

CAS No.: 2140-46-7

25-Hydroxycholesterol (25-HC)

Catalog No.: PC-21149Not For Human Use, Lab Use Only.

25-Hydroxycholesterol (25-HC) is a specific sterol regulatory element-binding proteins (SREBP-1) inhibitor, decreases SREBP-1 protein level in cells.

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Biological Activity

25-Hydroxycholesterol (25-HC) is a specific sterol regulatory element-binding proteins (SREBP-1) inhibitor, decreases SREBP-1 protein level in cells.

Physicochemical Properties

M.Wt 402.66
Formula C27H46O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol

References

1. Demoulin JB, et al. J Biol Chem. 2004 Aug 20;279(34):35392-402.

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