27-hydroxycholesterol | SERM | Probechem Biochemicals

Chemical Structure : 27-hydroxycholesterol

CAS No.: 20380-11-4

27-hydroxycholesterol (27HC, 27-OHC)

Catalog No.: PC-22707Not For Human Use, Lab Use Only.

27-Hydroxycholesterol (27-OHC, 27HC) is a selective estrogen receptor (ER) modulator and an agonist of the liver X receptor (LXR), regulates both gene transcription and cell proliferation in cellular models of breast cancer.

Packing	Price	Stock
5 mg	$158	In stock
10 mg	$248	In stock
25 mg	$428	In stock
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Biological Activity

Physicochemical Properties

M.Wt	402.66
Formula	C27H46O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(3S,8S,9S,10R,13R,14S,17R)-17-((2R,6R)-7-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol

References

1. Ye H, et al. Sci Adv. 2024 Jul 12;10(28):eadi4746.

2. DuSell CD, et al. Mol Endocrinol. 2008 Jan;22(1):65-77.

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27-hydroxycholesterol (27HC, 27-OHC)

Biological Activity

Physicochemical Properties

References

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