Chemical Structure : 27-hydroxycholesterol
CAS No.: 20380-11-4
Catalog No.: PC-22707Not For Human Use, Lab Use Only.
27-Hydroxycholesterol (27-OHC, 27HC) is a selective estrogen receptor (ER) modulator and an agonist of the liver X receptor (LXR), regulates both gene transcription and cell proliferation in cellular models of breast cancer.
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27-Hydroxycholesterol (27-OHC, 27HC) is a selective estrogen receptor (ER) modulator and an agonist of the liver X receptor (LXR), regulates both gene transcription and cell proliferation in cellular models of breast cancer.
| M.Wt | 402.66 | |
| Formula | C27H46O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(3S,8S,9S,10R,13R,14S,17R)-17-((2R,6R)-7-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol |
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1. Ye H, et al. Sci Adv. 2024 Jul 12;10(28):eadi4746.
2. DuSell CD, et al. Mol Endocrinol. 2008 Jan;22(1):65-77.

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