2800Z | SIRT7 inhibitor | Probechem Biochemicals

Chemical Structure : 2800Z

2800Z (SIRT7 inhibitor 2800Z)

Catalog No.: PC-20270Not For Human Use, Lab Use Only.

2800Z is a specific SIRT7 inhibitor, significantly inhibits SIRT7 deacetylation activity without effects on SIRT1 and SIRT6 activities, induces apoptosis and increases chemosensitivity to sorafenib in human liver cancer.

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Biological Activity

2800Z is a specific SIRT7 inhibitor, significantly inhibits SIRT7 deacetylation activity without effects on SIRT1 and SIRT6 activities, induces apoptosis and increases chemosensitivity to sorafenib in human liver cancer.

Physicochemical Properties

M.Wt	547.61
Formula	C30H33N3O7
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(3-(3,4-dimethoxyphenethyl)-1-(3-methoxyphenyl)-2,5-dioxoimidazolidin-4-yl)-N-(4-ethoxyphenyl)acetamide

References

1. Chen Zhang, et al. Front Cell Dev Biol. 2022 Jan 31;9:813233.

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2800Z (SIRT7 inhibitor 2800Z)

Biological Activity

Physicochemical Properties

References

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