| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-35760 |
MDL-800
|
2275619-53-7 |
MDL-800 (MDL800) is a first-in-class, selective, cellular active SIRT6 allosteric activator, increases SIRT6 deacetylation activity with EC50 of 10.3 uM in RHKK-ac-AMC and FDL assays. |
| PC-60123 |
SirReal2
|
1848251-24-0 |
SirReal2 (MZ25) is a novel potent, selective Sirt2 inhibitor with IC50 of 0.435 uM. |
| PC-38584 |
SIRT6 activator 12q
|
2601734-99-8 |
SIRT6 activator 12q (Compound 12q) is a potent, selective SIRT6 activator with EC1.5 value of 0.58 μM and EC50 value of 5.35 μM against SIRT6-dependent peptide deacetylation in FLUOR DE LYS assay. |
| PC-38580 |
SIRT6 activator CL5D
|
2488745-53-3 |
SIRT6 activator CL5D is a novel small-molecule activator of SIRT6 deacetylation, stimulates 4-fold activation of SIRT6 (1 uM) against H3K9ac (20 uM) at 3 uM. |
| PC-38543 |
AGK2
|
304896-28-4 |
AGK2 is a cell-permeable, selective inhibitor of SIRT2 with IC50 of 3.2 uM, shows minimally affects either SIRT1 or SIRT3 at 10-fold higher levels. |
| PC-38474 |
4-bromo-Resveratrol
|
1224713-90-9 |
4'-bromo-resveratrol (4'-BR) is a dual small molecule inhibitor of SIRT1 and SIRT3, inhibits melanoma cell growth through mitochondrial metabolic reprogramming. |
| PC-38461 |
SIRT7 inhibitor 97491
|
1807758-81-1 |
SIRT7 inhibitor 97491 is a novel specific inhibitor of SIRT7 with IC50 of 0.325 uM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. |
