| Cat. No. |
Product Name |
Information |
| PC-49474 |
SCIC2.1
SIRT1 activator
|
SCIC2.1 is a potent small molecule SIRT1 activator (175%, AC50=36.8 uM), directly binds SIRT1 and protects SIRT1 from thermal degradation. |
| PC-38584 |
SIRT6 activator 12q
SIRT6 activator
|
SIRT6 activator 12q (Compound 12q) is a potent, selective SIRT6 activator with EC1.5 value of 0.58 μM and EC50 value of 5.35 μM against SIRT6-dependent peptide deacetylation in FLUOR DE LYS assay. |
| PC-38580 |
SIRT6 activator CL5D
SIRT6 activator
|
SIRT6 activator CL5D is a novel small-molecule activator of SIRT6 deacetylation, stimulates 4-fold activation of SIRT6 (1 uM) against H3K9ac (20 uM) at 3 uM. |
| PC-38474 |
4-bromo-Resveratrol
Sirtuin inhibitor
|
4'-bromo-resveratrol (4'-BR) is a dual small molecule inhibitor of SIRT1 and SIRT3, inhibits melanoma cell growth through mitochondrial metabolic reprogramming. |
| PC-72774 |
SIRT2 inhibitor 56
SIRT2 inhibitor
|
SIRT2 inhibitor 56 is a potent selective SIRT2 inhibitor with IC50 of 780 nM. |
| PC-72773 |
SIRT2 inhibitor 55
SIRT2 inhibitor
|
SIRT2 inhibitor 55 is a potent and selective SIRT2 inhibitor with IC50 of 250 nM. |
| PC-72772 |
SIRT3 inhibitor 8
SIRT3 inhibitor
|
SIRT3 inhibitor 8 is a SIRT3 selective inhibitor with IC50 of 6 uM, 6.8- and 5.3-fold selectivity for SIRT3 versus SIRT1 and SIRT2. |
| PC-72767 |
SIRT5 inhibitor 49
SIRT5 inhibitor
|
SIRT5 inhibitor 49 (Sirt5-i) is a potent and specific SIRT5 inhibitor with IC50 of 0.11 uM. |
| PC-72766 |
SIRT5 inhibitor 32
SIRT5 inhibitor
|
SIRT5 inhibitor 32 is an efficient, cellularly active small molecule that targets SIRT5. |
