| Cat. No. |
Product Name |
Information |
| PC-21305 |
SirReal1.1
Sirtuin 2 inhibitor
|
SirReal1.1 is a potent, selective inhibitor of Sirtuin 2 (Sirt2) with IC50 of 0.16 uM. |
| PC-21165 |
EX-527
SirT1 inhibitor
|
Selisistat (EX-527) is is a potent and selective SirT1 (Sir2 in Drosophila melanogaster) inhibitor with IC50 of 123 nM for SirT1. |
| PC-21146 |
SIRT2 inhibitor 33a
Sirtuin 2 inhibitor
|
SIRT2 inhibitor 33a is a potent, specific Sirtuin 2 (SIRT2) inhibitor with IC50 of 1.0 uM, no activity against SIRT1 and SIRT3 (IC50>100 uM). |
| PC-21145 |
SIRT2 inhibitor 33i
Sirtuin 2 inhibitor
|
SIRT2 inhibitor 33i is a potent, specific Sirtuin 2 (SIRT2) inhibitor with IC50 of 0.57 uM, no activity against SIRT1 and SIRT3 (IC50>100 uM). |
| PC-21061 |
ADTL-SA1215
SIRT3 activator
|
ADTL-SA1215 is a small-molecule activator of SIRT3 with EC50 of 0.21 uM, specifically activates SIRT3 but not SIRT1, SIRT2, and SIRT5. |
| PC-21027 |
LC-0296
SIRT3 inhibitor
|
LC-0296 (LC0296) is a selective sirtuin-3 (SIRT3) inhibitor with IC50 of 3.6 uM, shows 20- and 10-fold selectivity over SIRT1 and SIRT2 respectively. |
| PC-21014 |
FLS-359
SIRT2 inhibitor
|
FLS-359 (FLS-359) is a selective, allosteric inhibitor of sirtuin 2 (SIRT2) deacetylase activity with IC50 of 3 uM, shows no activity against SIRT1 and SIRT3, exhibits broad-spectrum antiviral activity. |
| PC-72774 |
SIRT2 inhibitor 56
SIRT2 inhibitor
|
SIRT2 inhibitor 56 is a potent selective SIRT2 inhibitor with IC50 of 780 nM. |
| PC-72773 |
SIRT2 inhibitor 55
SIRT2 inhibitor
|
SIRT2 inhibitor 55 is a potent and selective SIRT2 inhibitor with IC50 of 250 nM. |
| PC-72772 |
SIRT3 inhibitor 8
SIRT3 inhibitor
|
SIRT3 inhibitor 8 is a SIRT3 selective inhibitor with IC50 of 6 uM, 6.8- and 5.3-fold selectivity for SIRT3 versus SIRT1 and SIRT2. |
| PC-72767 |
SIRT5 inhibitor 49
SIRT5 inhibitor
|
SIRT5 inhibitor 49 (Sirt5-i) is a potent and specific SIRT5 inhibitor with IC50 of 0.11 uM. |
| PC-72766 |
SIRT5 inhibitor 32
SIRT5 inhibitor
|
SIRT5 inhibitor 32 is an efficient, cellularly active small molecule that targets SIRT5. |
