| Cat. No. |
Product Name |
Information |
| PC-60122 |
MZ242
SIRT2 inhibitor
|
MZ242 is a novel potent, selective Sirt2 inhibitor with IC50 of 0.118 uM, displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM). |
| PC-42642 |
SRT 1720
SIRT1 activator
|
SRT 1720 is a potent, selective SIRT1 activator with EC1.5 of 0.16 uM. |
| PC-45037 |
AK-7
SIRT2 inhibitor
|
AK-7 is a potent, selective and brain-permeable SIRT2 inhibitor with IC50 of 15.5 uM. |
| PC-42395 |
AK-1
SIRT2 inhibitor
|
AK-1 is a potent, selective and brain-permeable SIRT2 inhibitor with IC50 of 12.5 uM. |
| PC-42309 |
Salermide
Sirtuin inhibitor
|
Salermide is a potent Sirtuin inhibitor with IC50 of 76 and 45 uM for SIRT1 and SIRT2, respectively. |
| PC-22465 |
MI-44
SIRT3 inhibitor
|
MI-44 is a small molecular inhibitor of SIRT, induces apoptosis in breast cancer cells. |
| PC-22464 |
MI-217
SIRT3 inhibitor
|
MI-217 is a small molecular inhibitor of SIRT3, induces apoptosis in breast cancer cells. |
| PC-22377 |
3-TYP
SIRT3 inhibitor
|
3-TYP is a specfiic small molecule inhibitor of Sirtuin 3 (SIRT3) with IC50 of 38 uM, selectively inhibits Sirt3 over Sirt1 and Sirt2 and is more potent than nicotinamid. |
| PC-22371 |
Honokiol
SIRT3 activator
|
Honokiol (NSC 293100) is a natural biphenolic compound derived from the bark of magnolia trees, directly binds to SIRT3 and is an effective activator of deacetylase SIRT3, shows anti-inflammatory, anti-oxidative, anti-tumour and neuroprotective properties. |
| PC-22370 |
2-APQC
SIRT3 activator
|
2-APQC is a specific, small-molecule activator of Sirtuin-3 (SIRT3), binds to (SPR KD=2.76 uM) and activates SIRT3 deacetylation activity. |
| PC-22069 |
SIRT3 activator MY-13
SIRT3 activator
|
SIRT3 activator MY-13 is a small-molecule activator of SIRT3, inhibits CRC cell proliferation and migration. |
| PC-21902 |
SRT1720 hydrochloride
SIRT1 activator
|
SRT 1720 Hcl is a potent, selective SIRT1 activator with EC1.5 of 0.16 uM. |
