| Cat. No. |
Product Name |
Information |
| PC-60825 |
YK-3-237
SIRT1 activator
|
YK-3-237 is a small molecule sirtuin-1 (SIRT1) activator that reduces acetylation of mutant 53 and exhibits anti-proliferative effects against TNBC cells carrying mutant p53. |
| PC-70105 |
Tenovin-D3
SIRT2 inhibitor
|
Tenovin-D3 is a selective, small-molecule inhibitor of sirtuin SIRT2 with IC50 of 21.8 uM. |
| PC-60124 |
SirReal1
Sirt2 inhibitor
|
SirReal1 is novel potent, selective Sirtuin 2 (Sirt2) inhibitor with IC50 of 3.745 uM, displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM). |
| PC-60123 |
SirReal2
Sirt2 inhibitor
|
SirReal2 (MZ25) is a novel potent, selective Sirtuin 2 (Sirt2) inhibitor with IC50 of 0.435 uM. |
| PC-60122 |
MZ242
SIRT2 inhibitor
|
MZ242 is a novel potent, selective Sirt2 inhibitor with IC50 of 0.118 uM, displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM). |
| PC-42642 |
SRT 1720
SIRT1 activator
|
SRT 1720 is a potent, selective SIRT1 activator with EC1.5 of 0.16 uM. |
| PC-45037 |
AK-7
SIRT2 inhibitor
|
AK-7 is a potent, selective and brain-permeable SIRT2 inhibitor with IC50 of 15.5 uM. |
| PC-42395 |
AK-1
SIRT2 inhibitor
|
AK-1 is a potent, selective and brain-permeable SIRT2 inhibitor with IC50 of 12.5 uM. |
| PC-42309 |
Salermide
Sirtuin inhibitor
|
Salermide is a potent Sirtuin inhibitor with IC50 of 76 and 45 uM for SIRT1 and SIRT2, respectively. |
| PC-23240 |
SIRT6 inhibitor 5a
SIRT6 inhibitor
|
SIRT6 inhibitor 5a is a small molecule inhibitor of SIRT6 with IC50 of 4.93 uM. |
| PC-22976 |
SJ-106C
SIRT3 inhibitor
|
SJ-106C is a specific mitochondria-targeted SIRT3 inhibitor with IC50 of 0.49 uM, suppresses DLBCL tumor growth. |
| PC-22579 |
YZL-51N
SIRT7 inhibitor
|
YZL-51N is a potent, selective, NAD+ competitive SIRT7 inhibitor with IC50 of 12.7 uM in Fluor de Lys (FDL) assays, inhibits SIRT7-mediated H3K18ac deacetylation with EC50 of 13.5 uM in dot blot assays. |
