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MZ242

Chemical Structure : MZ242

CAS No.: 1862238-01-4

MZ242 (MZ-242, MZ 242)

Catalog No.: PC-60122Not For Human Use, Lab Use Only.

MZ242 is a novel potent, selective Sirt2 inhibitor with IC50 of 0.118 uM, displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MZ242 is a novel potent, selective Sirt2 inhibitor with IC50 of 0.118 uM, displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM).

    Physicochemical Properties

    M.Wt 525.646
    Formula C24H27N7O3S2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-((4,6-dimethylpyrimidin-2-yl)thio)-N-(5-(3-((1-(2-methoxyethyl)-1H-1,2,3-triazol-4-yl)methoxy)benzyl)thiazol-2-yl)acetamide

    References

    1. Szabó A, et al. Sci Rep. 2017 Dec 6;7(1):17070.

    2. Schiedel M, et al. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6.

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