MZ242 |CAS: 1862238-01-4 Probechem Biochemicals

Chemical Structure : MZ242

Catalog No.: PC-60122Not For Human Use, Lab Use Only.

MZ242 is a novel potent, selective Sirt2 inhibitor with IC50 of 0.118 uM, displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM).

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Biological Activity

MZ242 is a novel potent, selective Sirt2 inhibitor with IC50 of 0.118 uM, displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM).

M.Wt	525.646
Formula	C24H27N7O3S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((4,6-dimethylpyrimidin-2-yl)thio)-N-(5-(3-((1-(2-methoxyethyl)-1H-1,2,3-triazol-4-yl)methoxy)benzyl)thiazol-2-yl)acetamide

1. Szabó A, et al. Sci Rep. 2017 Dec 6;7(1):17070.

2. Schiedel M, et al. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6.