Chemical Structure : SRT3025
CAS No.:
2070015-26-6
SRT3025
(SRT-3025, SRT 3025)
Catalog No. : PC-63006Not For Human Use, Lab Use Only.
SRT3025 is a potent, orally active SIRT1 activator that activates wild-type Sirt1 protein, but not the Sirt1 mutant E230K.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6300601
Biological Activity
SRT3025 is a potent, orally active SIRT1 activator that activates wild-type Sirt1 protein, but not the Sirt1 mutant E230K.
Physicochemical Properties
M.Wt
606.2
Formula
C31H32ClN5O2S2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
5-(3-methoxypropyl)-2-phenyl-N-(2-(6-(pyrrolidin-1-ylmethyl)thiazolo[5,4-b]pyridin-2-yl)phenyl)thiazole-4-carboxamide hydrochloride
References
1. Miranda MX, et al. Eur Heart J.
2. Chini CC, et al. Clin Cancer Res
3. Artsi H, et al. Endocrinology
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