SirReal1 |CAS:801227-82-7 Probechem Biochemicals

Chemical Structure : SirReal1

SirReal1 (SirReal 1)

Catalog No.: PC-60124Not For Human Use, Lab Use Only.

SirReal1 is novel potent, selective Sirtuin 2 (Sirt2) inhibitor with IC50 of 3.745 uM, displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM).

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Biological Activity

SirReal1 is novel potent, selective Sirtuin 2 (Sirt2) inhibitor with IC50 of 3.745 uM, displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM).

Physicochemical Properties

M.Wt	370.489
Formula	C18H18N4OS2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5-benzylthiazol-2-yl)-2-((4,6-dimethylpyrimidin-2-yl)thio)acetamide

References

1. Schiedel M, et al. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6.

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SirReal1 (SirReal 1)

Biological Activity

Physicochemical Properties

References

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