| Cat. No. |
Product Name |
Information |
| PC-22465 |
MI-44
SIRT3 inhibitor
|
MI-44 is a small molecular inhibitor of SIRT, induces apoptosis in breast cancer cells. |
| PC-22464 |
MI-217
SIRT3 inhibitor
|
MI-217 is a small molecular inhibitor of SIRT3, induces apoptosis in breast cancer cells. |
| PC-22377 |
3-TYP
SIRT3 inhibitor
|
3-TYP is a specfiic small molecule inhibitor of Sirtuin 3 (SIRT3) with IC50 of 38 uM, selectively inhibits Sirt3 over Sirt1 and Sirt2 and is more potent than nicotinamid. |
| PC-22371 |
Honokiol
SIRT3 activator
|
Honokiol (NSC 293100) is a natural biphenolic compound derived from the bark of magnolia trees, directly binds to SIRT3 and is an effective activator of deacetylase SIRT3, shows anti-inflammatory, anti-oxidative, anti-tumour and neuroprotective properties. |
| PC-22370 |
2-APQC
SIRT3 activator
|
2-APQC is a specific, small-molecule activator of Sirtuin-3 (SIRT3), binds to (SPR KD=2.76 uM) and activates SIRT3 deacetylation activity. |
| PC-22069 |
SIRT3 activator MY-13
SIRT3 activator
|
SIRT3 activator MY-13 is a small-molecule activator of SIRT3, inhibits CRC cell proliferation and migration. |
| PC-21902 |
SRT1720 hydrochloride
SIRT1 activator
|
SRT 1720 Hcl is a potent, selective SIRT1 activator with EC1.5 of 0.16 uM. |
| PC-21901 |
Sirtinol
Sirtuin inhibitor
|
Sirtinol is a small molecule sirtuin (SIRT) inhibitor with IC50 of 48 μM, 57.7 μM and 131 μM for ySir2, hSIRT2 and hSIRT2, respectively. |
| PC-21890 |
SIRT6 inhibitor S6
SIRT6 inhibitor
|
SIRT6 inhibitor S6 (SIRT6-IN-1) is a selective SIRT6 inhibitor with IC50 of 106 nM, 114 nM and 314 nM for SIRT6, SIRT2 and SIRT1 respectively. |
| PC-21715 |
UBCS373
Sirtuin 4 inhibitor
|
UBCS373 (Sirt4 inhibitor 69) is a highly isoform selective inhibitor of mitochondrial deacylase Sirtuin 4 (Sirt4) with IC50 of 16 uM. |
| PC-21714 |
UBCS385
Sirtuin 4 inhibitor
|
UBCS385 (Sirt4 inhibitor 60) is a potent, selective inhibitor of mitochondrial deacylase Sirtuin 4 (Sirt4) with IC50 of 0.9 uM. |
| PC-21306 |
SirReal1.2
Sirtuin 2 inhibitor
|
SirReal1.2 is a potent, selective inhibitor of Sirtuin 2 (Sirt2) with IC50 of 0.12 uM. |
