| Cat. No. |
Product Name |
Information |
| PC-21902 |
SRT1720 hydrochloride
SIRT1 activator
|
SRT 1720 Hcl is a potent, selective SIRT1 activator with EC1.5 of 0.16 uM. |
| PC-21901 |
Sirtinol
Sirtuin inhibitor
|
Sirtinol is a small molecule sirtuin (SIRT) inhibitor with IC50 of 48 μM, 57.7 μM and 131 μM for ySir2, hSIRT2 and hSIRT2, respectively. |
| PC-21890 |
SIRT6 inhibitor S6
SIRT6 inhibitor
|
SIRT6 inhibitor S6 (SIRT6-IN-1) is a selective SIRT6 inhibitor with IC50 of 106 nM, 114 nM and 314 nM for SIRT6, SIRT2 and SIRT1 respectively. |
| PC-21715 |
UBCS373
Sirtuin 4 inhibitor
|
UBCS373 (Sirt4 inhibitor 69) is a highly isoform selective inhibitor of mitochondrial deacylase Sirtuin 4 (Sirt4) with IC50 of 16 uM. |
| PC-21714 |
UBCS385
Sirtuin 4 inhibitor
|
UBCS385 (Sirt4 inhibitor 60) is a potent, selective inhibitor of mitochondrial deacylase Sirtuin 4 (Sirt4) with IC50 of 0.9 uM. |
| PC-21306 |
SirReal1.2
Sirtuin 2 inhibitor
|
SirReal1.2 is a potent, selective inhibitor of Sirtuin 2 (Sirt2) with IC50 of 0.12 uM. |
| PC-21305 |
SirReal1.1
Sirtuin 2 inhibitor
|
SirReal1.1 is a potent, selective inhibitor of Sirtuin 2 (Sirt2) with IC50 of 0.16 uM. |
| PC-21165 |
EX-527
SirT1 inhibitor
|
Selisistat (EX-527) is is a potent and selective SirT1 (Sir2 in Drosophila melanogaster) inhibitor with IC50 of 123 nM for SirT1. |
| PC-21146 |
SIRT2 inhibitor 33a
Sirtuin 2 inhibitor
|
SIRT2 inhibitor 33a is a potent, specific Sirtuin 2 (SIRT2) inhibitor with IC50 of 1.0 uM, no activity against SIRT1 and SIRT3 (IC50>100 uM). |
| PC-21145 |
SIRT2 inhibitor 33i
Sirtuin 2 inhibitor
|
SIRT2 inhibitor 33i is a potent, specific Sirtuin 2 (SIRT2) inhibitor with IC50 of 0.57 uM, no activity against SIRT1 and SIRT3 (IC50>100 uM). |
| PC-21061 |
ADTL-SA1215
SIRT3 activator
|
ADTL-SA1215 is a small-molecule activator of SIRT3 with EC50 of 0.21 uM, specifically activates SIRT3 but not SIRT1, SIRT2, and SIRT5. |
| PC-21027 |
LC-0296
SIRT3 inhibitor
|
LC-0296 (LC0296) is a selective sirtuin-3 (SIRT3) inhibitor with IC50 of 3.6 uM, shows 20- and 10-fold selectivity over SIRT1 and SIRT2 respectively. |
