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Rhynchophylline

Chemical Structure : Rhynchophylline

CAS No.: 76-66-4

Rhynchophylline

Catalog No.: PC-24360Not For Human Use, Lab Use Only.

Rhyncholphylline is an alkaloid compound isolated from Uncaria rhynchophyllum and EphA4 inhibitor, also is a selective Sirtuin 3 (SIRT3) agonist, prevents mitochondrial dysfunction by regulating the SIRT3/SOD2 pathway.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Rhyncholphylline is an alkaloid compound isolated from Uncaria rhynchophyllum and EphA4 inhibitor, also is a selective Sirtuin 3 (SIRT3) agonist, prevents mitochondrial dysfunction by regulating the SIRT3/SOD2 pathway.

Physicochemical Properties

M.Wt 384.48
Formula C22H28N2O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Methyl (E)-2-((3R,6'R,7'S,8a'S)-6'-ethyl-2-oxo-2',3',6',7',8',8a'-hexahydro-5'H-spiro[indoline-3,1'-indolizin]-7'-yl)-3-methoxyacrylate

References

1. Lin L, et al. Br J Pharmacol. 2025 Mar 31. doi: 10.1111/bph.70032.

2. Fu AK, et al. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9959-64.

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