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Chemical Structure : SRT1720 hydrochloride
CAS No.: 1001645-58-4
Catalog No.: PC-21902Not For Human Use, Lab Use Only.
SRT 1720 Hcl is a potent, selective SIRT1 activator with EC1.5 of 0.16 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $128 | In stock | |
| 50 mg | $188 | In stock | |
| 100 mg | $298 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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SRT1720 hydrochloride is a potent, selective SIRT1 activator with EC1.5 of 0.16 uM.
SRT 1720 displays good selectivity for activation of SIRT1 versus SIRT2 (EC1.5=37 uM) and SIRT3 (EC1.5>300 uM).
SRT 1720 is 1,000-fold more potent than resveratrol.
SRT 1720 improves insulin sensitivity, lower plasma glucose, and increases mitochondrial capacity in obese mice model.
| M.Wt | 506.02 | |
| Formula | C25H24ClN7OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(2-(3-(Piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)quinoxaline-2-carboxamide hydrochloride |
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1. Milne JC, et al. Nature. 2007 Nov 29;450(7170):712-6.
2. Pacholec M, et al. J Biol Chem. 2010 Mar 12;285(11):8340-51.
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