40569Z | SIRT7 inhibitor | Probechem Biochemicals

Chemical Structure : 40569Z

40569Z (SIRT7 inhibitor 40569Z)

Catalog No.: PC-20271Not For Human Use, Lab Use Only.

40569Z is a specific SIRT7 inhibitor, significantly inhibits SIRT7 deacetylation activity without effects on SIRT1 and SIRT6 activities, induces apoptosis and increases chemosensitivity to sorafenib in human liver cancer.

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Biological Activity

40569Z is a specific SIRT7 inhibitor, significantly inhibits SIRT7 deacetylation activity without effects on SIRT1 and SIRT6 activities, induces apoptosis and increases chemosensitivity to sorafenib in human liver cancer.

Physicochemical Properties

M.Wt	667.77
Formula	C32H34FN5O6S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	diethyl (R)-5-(2-((5-((3-fluorobenzamido)methyl)-4-phenethyl-4H-1,2,4-triazol-3-yl)thio)propanamido)-3-methylthiophene-2,4-dicarboxylate

References

1. Chen Zhang, et al. Front Cell Dev Biol. 2022 Jan 31;9:813233.

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40569Z (SIRT7 inhibitor 40569Z)

Biological Activity

Physicochemical Properties

References

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