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3-TYP

Chemical Structure : 3-TYP

CAS No.: 120241-79-4

3-TYP (SIRT3 inhibitor 3-TYP)

Catalog No.: PC-22377Not For Human Use, Lab Use Only.

3-TYP is a specfiic small molecule inhibitor of Sirtuin 3 (SIRT3) with IC50 of 38 uM, selectively inhibits Sirt3 over Sirt1 and Sirt2 and is more potent than nicotinamid.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

3-TYP is a specfiic small molecule inhibitor of Sirtuin 3 (SIRT3) with IC50 of 38 uM, selectively inhibits Sirt3 over Sirt1 and Sirt2 and is more potent than nicotinamid.

Physicochemical Properties

M.Wt 146.15
Formula C7H6N4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(1H-1,2,3-Triazol-4-yl)pyridine

References

1. Galli U, et al. Eur J Med Chem. 2012 Sep;55:58-66.

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