3M-003 |CAS:162397-26-4 Probechem Biochemicals

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Chemical Structure : 3M-003

3M-003 (3M003)

Catalog No.: PC-70304Not For Human Use, Lab Use Only.

3M-003 is a potent TLR7/8 agonist that induces robust production of the Th1-polarizing cytokines TNF-alpha and IL-12 from neonatal antigen-presenting cells (APCs).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

3M-003 is a potent TLR7/8 agonist that induces robust production of the Th1-polarizing cytokines TNF-alpha and IL-12 from neonatal antigen-presenting cells (APCs).

Physicochemical Properties

M.Wt	318.421
Formula	C17H26N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-Amino-2-(ethoxymethyl)-6,7,8,9-tetrahydro-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol

References

1. Levy O, et al. Blood. 2006 Aug 15;108(4):1284-90.

2. Gorski KS, et al. Int Immunol. 2006 Jul;18(7):1115-26.

3. Gorden KB, et al. J Immunol. 2005 Feb 1;174(3):1259-68.

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3M-003 (3M003)

Biological Activity

Physicochemical Properties

References

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