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3M-003

Chemical Structure : 3M-003

CAS No.: 162397-26-4

3M-003 (3M003)

Catalog No.: PC-70304Not For Human Use, Lab Use Only.

3M-003 is a potent TLR7/8 agonist that induces robust production of the Th1-polarizing cytokines TNF-alpha and IL-12 from neonatal antigen-presenting cells (APCs).

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    Biological Activity

    3M-003 is a potent TLR7/8 agonist that induces robust production of the Th1-polarizing cytokines TNF-alpha and IL-12 from neonatal antigen-presenting cells (APCs).

    Physicochemical Properties

    M.Wt 318.421
    Formula C17H26N4O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-Amino-2-(ethoxymethyl)-6,7,8,9-tetrahydro-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol

    References

    1. Levy O, et al. Blood. 2006 Aug 15;108(4):1284-90.

    2. Gorski KS, et al. Int Immunol. 2006 Jul;18(7):1115-26.

    3. Gorden KB, et al. J Immunol. 2005 Feb 1;174(3):1259-68.

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