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Chemical Structure : 3M-011
Catalog No.: PC-70305Not For Human Use, Lab Use Only.
3M-011 is a potent TLR7/8 agonist and cytokine inducer.
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3M-011 is a potent TLR7/8 agonist and cytokine inducer.
3M-011 stimulates type I interferon (IFN) and other cytokines such as TNF-alpha, IL-12, and IFN-gamma from rat peripheral blood mononuclear cells.
3M-011 induces IL-12 and COX-2 expression in mDC from HIV+ and HIV- individuals, and inhibits H3N2 influenza viral replication in the nasal cavity; potentiates NK cytotoxicity, and shows antitumor effects in scid/B6 mice and scid/NOD mice.
| M.Wt | 391.49 | |
| Formula | C18H25N5O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Martinson JA, et al. Cell Immunol. 2007 Nov-Dec;250(1-2):75-84.
2. Hammerbeck DM, et al. Antiviral Res. 2007 Jan;73(1):1-11.
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